Brain changes during isolation

An international crew began a 240-day journey of voluntary seclusion in November at the Institute of Biomedical Problems (IBMP) in Moscow, Russia. The SIRIUS-21 mission simulates a lunar expedition, including a Moon landing and a spacewalk, without ever leaving four locked chambers on Earth.

For eight months, volunteers are deprived of natural daylight and fresh air, and can only communicate with ground control and family via audio contact or email from a mockup spacecraft.

The crew of five is taking part in dozens of research studies on neuroscience, psychology, and immunology. Four European experiments are collecting scientific data on decision-making, performance and changes in the brain.

Our brain experiences changes under prolonged isolation and confinement. Alterations in how humans perceive the space around them, relate to others, and react to critical situations are at the heart of the BRAIVE experiment.